Showing posts with label GENETICS. Show all posts
Showing posts with label GENETICS. Show all posts
2007-09-06
Richard Dawkins, Galapagos Lectures
On an eco-tourist cruise to the Galapagos aboard the Santa Cruz, Richard Dawkins delivers several lectures on population genetics and the evolutionary process. Having read several of his books and watched most of his documentaries, I assumed I had just about exhausted his educational potential. This lecture series showed me the fallacy of this assumption. These are some of the best lectures I have heard on the subject, beautifully delivered as always by the eloquent professor. Available at Demonoid. Some lectures available at Google Video.
2007-06-02
DNA Discoverer has Personal Genome Sequenced
Nobel laureate James Waston, together with Francis Crick, discovered the double helix structure of DNA along with the mechanism by which it is the medium for Genetic information. The entire human genome was sequenced only 4 years ago as a large collaborative effort costing USD 3 billion over 13 years. Gene sequencing technology, like computing is advancing exponentially such that in 60 days Watson's genome was sequenced for under USD 1 million. A genome's information will fit on a single DVD.
Watson is an active proponent of human genetic engineering, what could be termed "eugenics." While many support the idea of genetic therapy to cure or prevent disease, Watson goes farther, supporting genetic engineering even for cosmetic purposes. This issue will more and more come to the forefront of public policy and debate, hopefully even overshadowing the Anna Nicole Smith's baby daddy controversy or Paris Hilton's jail sentencing. I fully support reproductive freedom with the limits that parents are taxed for bringing new people into the world (perhaps progressively) and parents and doctors punished if their genetic or fertility experiments result in undue or unnatural human suffering. The unfortunate result of this may be that the human genome experiences fads where some celebrity's genes become very quickly overrepresented in the population, but overall I expect people will wish to preserve large sections of their own genome in the next generation while tweaking out negative carcinogenic genes and aiming for healthy life extension in the next generation. Meanwhile the cult of the "organic" will come to encompass the human population where a natural and more diseased segment of the population will remain reproductively exclusive. If I had the choice and the technology were sufficiently developed so as to be well understood and extremely reliable, my offspring would probably not be organic. To quote Watson, "If every girl were beautiful, I think it would be great!"
Personal genome sequencing has more immediate implications for health care, preventative medicine, insurance, and medical economics, but that is a topic for another time.
Watson is an active proponent of human genetic engineering, what could be termed "eugenics." While many support the idea of genetic therapy to cure or prevent disease, Watson goes farther, supporting genetic engineering even for cosmetic purposes. This issue will more and more come to the forefront of public policy and debate, hopefully even overshadowing the Anna Nicole Smith's baby daddy controversy or Paris Hilton's jail sentencing. I fully support reproductive freedom with the limits that parents are taxed for bringing new people into the world (perhaps progressively) and parents and doctors punished if their genetic or fertility experiments result in undue or unnatural human suffering. The unfortunate result of this may be that the human genome experiences fads where some celebrity's genes become very quickly overrepresented in the population, but overall I expect people will wish to preserve large sections of their own genome in the next generation while tweaking out negative carcinogenic genes and aiming for healthy life extension in the next generation. Meanwhile the cult of the "organic" will come to encompass the human population where a natural and more diseased segment of the population will remain reproductively exclusive. If I had the choice and the technology were sufficiently developed so as to be well understood and extremely reliable, my offspring would probably not be organic. To quote Watson, "If every girl were beautiful, I think it would be great!"
Personal genome sequencing has more immediate implications for health care, preventative medicine, insurance, and medical economics, but that is a topic for another time.
2006-12-05
Genetic Diversity
New genetic data reveals what most of us already know intuitively, genetic diversity is much more varied and complex than previous studies and textbooks would suggest - statements like "We share 99.5% of our genes with one another." Previous studies did not properly measure the level of copies or deletions among individuals. The existence of high genetic variation makes sense given the large differences seen among humans, but similarly reflects the overall health of our species. Genetic diversity can be thought of as genetic wealth. Genetic poverty, a lack of diversity, comes from intense stress, isolation, or bottlenecking of a population which surely has occurred in the past for almost every species alive today. Indeed, the eugenicists of the twentieth century had their priorities completely backwards. This new understanding of genetic diversity will also help to better treat genetic diseases which are rapidly becoming the limiting factor on human health as infectious disease and malnutrition wane.
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